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KMID : 0921620130430040307
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Journal of Bacteriology and Virology
2013 Volume.43 No. 4 p.307 ~ p.316
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Molecular Characterization of Norovirus and Rotavirus in Outbreak of Acute Gastroenteritis in Seoul
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Oh Se-Ah
Park Sang-Hun
Ham Hee-Jin
Seung Hyun-Jung
Jang Jung-Im
Suh Sang-Won
Jo Suk-Ju
Choi Sung-Min
Jeong Hae-Sook
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Abstract
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Norovirus and rotavirus are important causes of acute nonbacterial gastroenteritis in communities worldwide. Genotypes of norovirus and rotavirus in stool samples, which were collected from patients, was determined by RT-PCR and ELISA. A total 4,484 stool samples (461 outbreak cases) collected during January 2010-April 2013 were analyzed. Four hundred thirty eight of samples were positive for norovirus. Twelve samples were positive for Rotavirus. Norovirus genotypes identified were nine kinds of G I genotype (G I -1, G I -2, G I -3, G I -4, G I -6, G I -7, G I -9, G I -12, G I -13) and nine kinds of G II genotype(G II -2, G II -4, G II -5, G II -6, G II -7, G II -11, G II -12, G II -15, G II -16). Rotavirus genotypes were G2P[4]. The results might be useful information for evaluating the epidemiological status of viral diarrhea in Seoul, and providing a strategy to prevent human norovirus, rotavirus and other threats to public health in Korea.
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KEYWORD
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Norovirus, Rotavirus, Genotypes, Gastroenteritis outbreak
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